One of the complex medicines for the therapy of ischemia, angina, the consequences of myocardial infarction and anxiety is Inderal. It has antihypertensive, anti-anginal and antiarrhythmic actions, normalizes the work of the heart muscle.
This beta-blocker causes rapid calming of the pulse, shortening of the heartbeat, and as a result, helps to cope with the panic attack and to normalize the emotional state.
That’s why in case of anxiety with the risk of development of panic attacks, doctors strongly recommend that you always carry a couple of Inderal tablets with you.
The drug contains propranolol as an active substance and is manufactured in the form of tablets, solution for injections and capsules.
The principle of the drug is based on an indiscriminate blocking of beta-adrenoreceptors, decreasing of the formation of cyclic adenosine monophosphate and the intake of calcium ions into the cell. Due to this, the negative inotropic effect is formed, contractility of the myocardium decreases, the pulse becomes less frequent.
Propranolol is included in the group of antiarrhythmic drugs of the second group. It reduces postinfarction lethality, prevents the development of headaches, the severity of tremor.
The use of the drug has a wide range of indications. The primary administrations of Inderal are diseases of the cardiovascular system: angina pectoris; arterial hypertension; sinus tachycardia; unstable angina; atrial tachyarrhythmia; supraventricular tachycardia; myocardial infarction; alcohol abstinence; ventricular extrasystole; essential tremor; thyrotoxic crisis; diffuse-toxic goiter; sympathoadrenal crises; pheochromocytoma; anxiety.
Dosing and Administration
Tablets and capsules are taken orally, the solution is used parenterally. Depending on the disease, the dose of the drug differs.
When you use Inderal for the treatment of anxiety or panic attacks, you must carefully monitor the dosage. Excessive use of Inderal threatens with serious health consequences. However, during a panic attack, you need to take the pill as soon as possible. For better assimilation and quick effect, it is necessary to put the tablet under the tongue, and allow it to dissolve in saliva.
During the treatment, you should regularly check the blood sugar level, monitor the pressure, pulse, electrocardiogram. In the elderly, monitoring of the state of the kidneys is necessary.
During the treatment with a drug, it is possible to display various side effects on the part of the body systems. These include: drowsiness, fatigue, nightmares, dizziness, weakness, tremor, paresthesia, lameness in Reye’s syndrome, depression, memory problems, confusion, hallucinations, asthenia, headaches, anxiety, myasthenia gravis; impaired vision, dry eyes, keratoconjunctivitis; arrhythmia, orthostatic hypotension, heart palpitations, sinus bradycardia, chest pain, angiospasm, coldness of the lower limbs; taste disorders, dry mouth, nausea, cholestasis, stomach pain, vomiting, stool disorders, darkening of urine, flatulence, hypersecretion of gastric juice; nasal congestion, bronchospasm, rhinitis, difficulty breathing, laryngospasm; hypoglycemia in the preparation of insulin, hyperglycemia; allergies, itching, rashes on the skin, hives; exacerbation of psoriasis, alopecia, increased sweating, skin hyperemia, alopecia; leukopenia, thrombocytopenia, agranulocytosis, hyperbilirubinemia; weakening of libido; back pain, arthralgia.
Contraindications for the drug are: cardiogenic shock; AV blockade; cardiomegaly; angina of Prinzmetal; sinus bradycardia of the ventricle; syndrome of weakness of the sinus node; metabolic acidosis; decompensated form of chronic heart failure; arterial hypotension; bronchial asthma; psoriasis; liver failure; myasthenia gravis; diabetes mellitus with ketoacidosis; gangrene.
Medication is prescribed with caution for depression, kidney pathology, Raynaud’s syndrome, allergies, in the elderly and children, with thyrotoxicosis.
It is not recommended to combine tranquilizers with Inderal. Such a combination only strengthens its effect on the nervous system. Also, the various intoxication of the body is not permissible, for example, because of alcohol. It is known that alcohol can reduce blood pressure, and when taking Inderal it is unacceptable.
With prolonged use of Inderal, it becomes necessary to constantly increase the dosage of the drug to achieve a positive effect. It is observed in almost all patients who have taken Inderal for a long time. The body is learning to resist substances, and more and more of Inderal is required to block receptors. Addiction to the drug is one of the reasons for canceling the drug. However, it is impossible to stop the reception abruptly, as this will lead to a significant deterioration in the patient’s condition like increased pressure, and a high risk of heart attack.
With the prolonged reception of Inderal, the body begins to act by adjusting to it. As a result, the patient’s adrenaline rises and the pulse increases. In order not to face such problems, it is necessary to reduce the dosage of the drug gradually, and then completely refuse to take it. After giving up the medication, the body will be able to adjust to the usual mode of operation.